北京哪个医院能治疗白癜风 http://baidianfeng.39.net/bdfby/yqyy/SCI
23August
PanouV,GadirajuM,WolinA,etal.FrequencyofGermlineMutationsinCancerSusceptibilityGenesinMalignantMesothelioma.Journalofclinicaloncology
fficialjournaloftheAmericanSocietyofClinicalOncology:JCO785204.
CorrespondingAuthors
/p>
JaneE.Churpek,MD,TheUniversityofChicago,SMarylandAve,MC,Chicago
Purpose目的
Theaimofthecurrentstudywastodeterminetheprevalenceandclinicalpredictorsofgermlinecancersusceptibilitymutationsinpatientswithmalignantmesothelioma(MM).
此次研究的目的是确定恶性间皮瘤（MM）患者的生殖系癌症易感性突变的患病率和临床预测因子。
Methods方法
Weperformedtargetedcaptureandnext-generationsequencingof85cancersusceptibilitygenesongermlineDNAfrompatientswithpleural,peritoneal,andtunicavaginalisMM.
我们对来自名胸膜、腹膜和鞘突的恶性间皮瘤患者的生殖系DNA的85个癌症易感基因进行了靶向捕捉和下一代测序。
Results结果
Twenty-fourgermlinemutationswereidentifiedin13genesin23(12%)ofpatients.BAP1mutationswerethemost
